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Replication timing networks reveal a link between transcription regulatory circuits and replication timing control

DNA replication occurs in a defined temporal order known as the replication timing (RT) program and is regulated during development, coordinated with 3D genome organization and transcriptional activity. However, transcription and RT are not sufficiently coordinated to predict each other, suggesting...

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Detalles Bibliográficos
Autores principales: Rivera-Mulia, Juan Carlos, Kim, Sebo, Gabr, Haitham, Chakraborty, Abhijit, Ay, Ferhat, Kahveci, Tamer, Gilbert, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724675/
https://www.ncbi.nlm.nih.gov/pubmed/31434679
http://dx.doi.org/10.1101/gr.247049.118