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A high resolution A-to-I editing map in the mouse identifies editing events controlled by pre-mRNA splicing

Pre-mRNA-splicing and adenosine to inosine (A-to-I) RNA-editing occur mostly cotranscriptionally. During A-to-I editing, a genomically encoded adenosine is deaminated to inosine by adenosine deaminases acting on RNA (ADARs). Editing-competent stems are frequently formed between exons and introns. Co...

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Detalles Bibliográficos
Autores principales: Licht, Konstantin, Kapoor, Utkarsh, Amman, Fabian, Picardi, Ernesto, Martin, David, Bajad, Prajakta, Jantsch, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724681/
https://www.ncbi.nlm.nih.gov/pubmed/31427386
http://dx.doi.org/10.1101/gr.242636.118