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N-glycosylation–dependent regulation of hK(2P)17.1 currents

Two pore-domain potassium (K(2P)) channels mediate potassium background currents that stabilize the resting membrane potential and facilitate action potential repolarization. In the human heart, hK(2P)17.1 channels are predominantly expressed in the atria and Purkinje cells. Reduced atrial hK(2P)17....

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Detalles Bibliográficos
Autores principales: Wiedmann, Felix, Schlund, Daniel, Voigt, Niels, Ratte, Antonius, Kraft, Manuel, Katus, Hugo A., Schmidt, Constanze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724686/
https://www.ncbi.nlm.nih.gov/pubmed/30969900
http://dx.doi.org/10.1091/mbc.E18-10-0687