Cargando…

The desmosome is a mesoscale lipid raft–like membrane domain

Desmogleins (Dsgs) are cadherin family adhesion molecules essential for epidermal integrity. Previous studies have shown that desmogleins associate with lipid rafts, but the significance of this association was not clear. Here, we report that the desmoglein transmembrane domain (TMD) is the primary...

Descripción completa

Detalles Bibliográficos
Autores principales: Lewis, Joshua D., Caldara, Amber L., Zimmer, Stephanie E., Stahley, Sara N., Seybold, Anna, Strong, Nicole L., Frangakis, Achilleas S., Levental, Ilya, Wahl, James K., Mattheyses, Alexa L., Sasaki, Takashi, Nakabayashi, Kazuhiko, Hata, Kenichiro, Matsubara, Yoichi, Ishida-Yamamoto, Akemi, Amagai, Masayuki, Kubo, Akiharu, Kowalczyk, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724694/
https://www.ncbi.nlm.nih.gov/pubmed/30943110
http://dx.doi.org/10.1091/mbc.E18-10-0649