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NK Cell Precursors in Human Bone Marrow in Health and Inflammation

NK cells are generated from hematopoietic stem cells (HSC) residing in the bone marrow (BM), similar to other blood cells. Development toward mature NK cells occurs largely outside the BM through travel of CD34+ and other progenitor intermediates toward secondary lymphoid organs. The BM harbors mult...

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Detalles Bibliográficos
Autores principales: Bozzano, Federica, Perrone, Carola, Moretta, Lorenzo, De Maria, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724745/
https://www.ncbi.nlm.nih.gov/pubmed/31555276
http://dx.doi.org/10.3389/fimmu.2019.02045