Inhibition of nSMase2 Reduces the Transfer of Oligomeric α-Synuclein Irrespective of Hypoxia

Recently, extracellular vesicles (EVs), such as exosomes, have been proposed to play an influential role in the cell-to-cell spread of neurodegenerative diseases, including the intercellular transmission of α-synuclein (α-syn). However, the regulation of EV biogenesis and its relation to Parkinson’s...

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Detalles Bibliográficos
Autores principales: Sackmann, Valerie, Sinha, Maitrayee Sardar, Sackmann, Christopher, Civitelli, Livia, Bergström, Joakim, Ansell-Schultz, Anna, Hallbeck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724746/
https://www.ncbi.nlm.nih.gov/pubmed/31555088
http://dx.doi.org/10.3389/fnmol.2019.00200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724746/
https://www.ncbi.nlm.nih.gov/pubmed/31555088
http://dx.doi.org/10.3389/fnmol.2019.00200

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