Vinculin and metavinculin exhibit distinct effects on focal adhesion properties, cell migration, and mechanotransduction

Vinculin (Vcn) is a ubiquitously expressed cytoskeletal protein that links transmembrane receptors to actin filaments, and plays a key role in regulating cell adhesion, motility, and force transmission. Metavinculin (MVcn) is a Vcn splice isoform that contains an additional exon encoding a 68-residu...

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Detalles Bibliográficos
Autores principales: Lee, Hyunna T., Sharek, Lisa, O’Brien, E. Timothy, Urbina, Fabio L., Gupton, Stephanie L., Superfine, Richard, Burridge, Keith, Campbell, Sharon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726196/
https://www.ncbi.nlm.nih.gov/pubmed/31483833
http://dx.doi.org/10.1371/journal.pone.0221962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726196/
https://www.ncbi.nlm.nih.gov/pubmed/31483833
http://dx.doi.org/10.1371/journal.pone.0221962

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