Mechanistic insights into the phosphoryl transfer reaction in cyclin-dependent kinase 2: A QM/MM study

Cyclin-dependent kinase 2 (CDK2) is an important member of the CDK family exerting its most important function in the regulation of the cell cycle. It catalyzes the transfer of the gamma phosphate group from an ATP (adenosine triphosphate) molecule to a Serine/Threonine residue of a peptide substrat...

Descripción completa

Detalles Bibliográficos
Autores principales: Recabarren, Rodrigo, Osorio, Edison H., Caballero, Julio, Tuñón, Iñaki, Alzate-Morales, Jans H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726203/
https://www.ncbi.nlm.nih.gov/pubmed/31483779
http://dx.doi.org/10.1371/journal.pone.0215793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726203/
https://www.ncbi.nlm.nih.gov/pubmed/31483779
http://dx.doi.org/10.1371/journal.pone.0215793

Ejemplares similares