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Evolution of CRISPR towards accurate and efficient mammal genome engineering

The evolution of genome editing technology based on CRISPR (clustered regularly interspaced short palindromic repeats) system has led to a paradigm shift in biological research. CRISPR/Cas9-guide RNA complexes enable rapid and efficient genome editing in mammalian cells. This system induces double-s...

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Detalles Bibliográficos
Autores principales: Ryu, Seuk-Min, Hur, Junseok W, Kim, Kyoungmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726207/
https://www.ncbi.nlm.nih.gov/pubmed/31234957
http://dx.doi.org/10.5483/BMBRep.2019.52.8.149