Cargando…

The use of a predictive statistical model to make a virtual control arm for a clinical trial

BACKGROUND: Randomized clinical trials compare participants receiving an experimental intervention to participants receiving standard of care (SOC). If one could predict the outcome for participants receiving SOC, a trial could be designed where all participants received the experimental interventio...

Descripción completa

Detalles Bibliográficos
Autores principales: Switchenko, Jeffrey M., Heeke, Arielle L., Pan, Tony C., Read, William L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726216/
https://www.ncbi.nlm.nih.gov/pubmed/31483824
http://dx.doi.org/10.1371/journal.pone.0221336