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The use of a predictive statistical model to make a virtual control arm for a clinical trial
BACKGROUND: Randomized clinical trials compare participants receiving an experimental intervention to participants receiving standard of care (SOC). If one could predict the outcome for participants receiving SOC, a trial could be designed where all participants received the experimental interventio...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726216/ https://www.ncbi.nlm.nih.gov/pubmed/31483824 http://dx.doi.org/10.1371/journal.pone.0221336 |