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Fetal programming of adrenal PNMT and hypertension by glucocorticoids in WKY rats is dose and sex-dependent

Biochemical changes in utero may alter normal fetal development, resulting in disease later in life, a phenomenon known as fetal programming. Recent epidemiological studies link fetal programming to negative health outcomes, such as low birth weight and hypertension in adulthood. Here, we used a WKY...

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Detalles Bibliográficos
Autores principales: Khurana, Sandhya, Grandbois, Julie, Tharmalingam, Sujeenthar, Murray, Alyssa, Graff, Kelly, Nguyen, Phong, Tai, T. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726223/
https://www.ncbi.nlm.nih.gov/pubmed/31483805
http://dx.doi.org/10.1371/journal.pone.0221719