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Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome

Introns are a prevalent feature of eukaryotic genomes, yet their origins and contributions to genome function and evolution remain mysterious. In budding yeast, repression of the highly transcribed intron-containing ribosomal protein genes (RPGs) globally increases splicing of non-RPG transcripts th...

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Detalles Bibliográficos
Autores principales: Talkish, Jason, Igel, Haller, Perriman, Rhonda J., Shiue, Lily, Katzman, Sol, Munding, Elizabeth M., Shelansky, Robert, Donohue, John Paul, Ares, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726248/
https://www.ncbi.nlm.nih.gov/pubmed/31437148
http://dx.doi.org/10.1371/journal.pgen.1008249