Prediction of MMP-9 inhibitory activity of N-hydroxy-α-phenylsulfonylacetamide derivatives by pharmacophore based modeling and 3-D QSAR studies

Matrix metalloproteinase-9 (MMP-9), also known as gelatinase B, is a MMP that is strongly associated with multiple cellular processes including proliferation, angiogenesis, and metastasis. Various studies have shown that N-hydroxy-α-phenylsulfonylacetamide (HPSAs) derivatives are promising and selec...

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Detalles Bibliográficos
Autores principales: Rathee, Dharmender, Lather, Viney, Dureja, Harish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726302/
https://www.ncbi.nlm.nih.gov/pubmed/31595232
http://dx.doi.org/10.1016/j.pbj.0000000000000006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726302/
https://www.ncbi.nlm.nih.gov/pubmed/31595232
http://dx.doi.org/10.1016/j.pbj.0000000000000006

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