Human umbilical cord blood monocytes, but not adult blood monocytes, rescue brain cells from hypoxic-ischemic injury: Mechanistic and therapeutic implications

Cord blood (CB) mononuclear cells (MNC) are being tested in clinical trials to treat hypoxic-ischemic (HI) brain injuries. Although early results are encouraging, mechanisms underlying potential clinical benefits are not well understood. To explore these mechanisms further, we exposed mouse brain or...

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Detalles Bibliográficos
Autores principales: Saha, Arjun, Patel, Sachit, Xu, Li, Scotland, Paula, Schwartzman, Jonathan, Filiano, Anthony J., Kurtzberg, Joanne, Balber, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726370/
https://www.ncbi.nlm.nih.gov/pubmed/31483780
http://dx.doi.org/10.1371/journal.pone.0218906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726370/
https://www.ncbi.nlm.nih.gov/pubmed/31483780
http://dx.doi.org/10.1371/journal.pone.0218906

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