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Astrocyte morphogenesis is dependent on BDNF signaling via astrocytic TrkB.T1

Brain-derived neurotrophic factor (BDNF) is a critical growth factor involved in the maturation of the CNS, including neuronal morphology and synapse refinement. Herein, we demonstrate astrocytes express high levels of BDNF’s receptor, TrkB (in the top 20 of protein-coding transcripts), with nearly...

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Detalles Bibliográficos
Autores principales: Holt, Leanne M, Hernandez, Raymundo D, Pacheco, Natasha L, Torres Ceja, Beatriz, Hossain, Muhannah, Olsen, Michelle L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726422/
https://www.ncbi.nlm.nih.gov/pubmed/31433295
http://dx.doi.org/10.7554/eLife.44667