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Astrocyte morphogenesis is dependent on BDNF signaling via astrocytic TrkB.T1
Brain-derived neurotrophic factor (BDNF) is a critical growth factor involved in the maturation of the CNS, including neuronal morphology and synapse refinement. Herein, we demonstrate astrocytes express high levels of BDNF’s receptor, TrkB (in the top 20 of protein-coding transcripts), with nearly...
Autores principales: | Holt, Leanne M, Hernandez, Raymundo D, Pacheco, Natasha L, Torres Ceja, Beatriz, Hossain, Muhannah, Olsen, Michelle L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726422/ https://www.ncbi.nlm.nih.gov/pubmed/31433295 http://dx.doi.org/10.7554/eLife.44667 |
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