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EPHA2 mutations with oncogenic characteristics in squamous cell lung cancer and malignant pleural mesothelioma

Squamous cell carcinoma (SCC) and malignant pleural mesothelioma (MPM) are thoracic malignancies with very poor prognosis and limited treatment options. It is an established fact that most of the solid tumors have overexpression of EPHA2 receptor tyrosine kinase. EPHA2 is known to exhibit opposing r...

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Detalles Bibliográficos
Autores principales: Tan, Yi-Hung Carol, Srivastava, Saumya, Won, Brian M., Kanteti, Rajani, Arif, Qudsia, Husain, Aliya N., Li, Hubert, Vigneswaran, Wickii T., Pang, Ka-Ming, Kulkarni, Prakash, Sattler, Martin, Vaidehi, Nagarajan, Mambetsariev, Isa, Kindler, Hedy L., Wheeler, Deric L., Salgia, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726628/
https://www.ncbi.nlm.nih.gov/pubmed/31484920
http://dx.doi.org/10.1038/s41389-019-0159-6