Phospholipase C-related catalytically inactive protein regulates cytokinesis by protecting phosphatidylinositol 4,5-bisphosphate from metabolism in the cleavage furrow

Cytokinesis is initiated by the formation and ingression of the cleavage furrow. Phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)] accumulation followed by RhoA translocation to the cleavage furrow are prerequisites for cytokinesis progression. Here, we investigated whether phospholipase C (PLC)-r...

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Detalles Bibliográficos
Autores principales: Asano, Satoshi, Ikura, Yasuka, Nishimoto, Mitsuki, Yamawaki, Yosuke, Hamao, Kozue, Kamijo, Keiju, Hirata, Masato, Kanematsu, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726632/
https://www.ncbi.nlm.nih.gov/pubmed/31484968
http://dx.doi.org/10.1038/s41598-019-49156-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726632/
https://www.ncbi.nlm.nih.gov/pubmed/31484968
http://dx.doi.org/10.1038/s41598-019-49156-3

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