CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis

The diverse expression pattern of CD36 reflects its multiple cellular functions. However, the roles of CD36 in colorectal cancer (CRC) remain unknown. Here, we discover that CD36 expression is progressively decreased from adenomas to carcinomas. CD36 loss predicts poor survival of CRC patients. In C...

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Detalles Bibliográficos
Autores principales: Fang, Yuan, Shen, Zhi-Yong, Zhan, Yi-Zhi, Feng, Xiao-Chuang, Chen, Ke-Li, Li, Yong-Sheng, Deng, Hai-Jun, Pan, Su-Ming, Wu, De-Hua, Ding, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726635/
https://www.ncbi.nlm.nih.gov/pubmed/31484922
http://dx.doi.org/10.1038/s41467-019-11662-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726635/
https://www.ncbi.nlm.nih.gov/pubmed/31484922
http://dx.doi.org/10.1038/s41467-019-11662-3

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