Cargando…
Interrogating Mutant Allele Expression via Customized Reference Genomes to Define Influential Cancer Mutations
Genetic alterations are essential for cancer initiation and progression. However, differentiating mutations that drive the tumor phenotype from mutations that do not affect tumor fitness remains a fundamental challenge in cancer biology. To better understand the impact of a given mutation within can...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726654/ https://www.ncbi.nlm.nih.gov/pubmed/31484939 http://dx.doi.org/10.1038/s41598-019-48967-8 |