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Combination treatment with n-3 polyunsaturated fatty acids and ursodeoxycholic acid dissolves cholesterol gallstones in mice

The increasing prevalence of cholesterol gallstone disease places an economic burden on the healthcare system. To identify novel therapeutics, we assessed the effects of n-3 polyunsaturated fatty acids (PUFA) in combination with UDCA in a mouse model of cholesterol gallstones. Gallstone dissolution,...

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Detalles Bibliográficos
Autores principales: Jang, Sung Ill, Fang, Sungsoon, Kim, Kwang Pyo, Ko, Younhee, Kim, Hyoseon, Oh, Jieun, Hong, Ga Young, Lee, Su Yeon, Kim, Joon Mee, Noh, Ilkoo, Lee, Dong Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726655/
https://www.ncbi.nlm.nih.gov/pubmed/31484954
http://dx.doi.org/10.1038/s41598-019-49095-z