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Lipid peroxidation increases hydrogen peroxide permeability leading to cell death in cancer cell lines that lack mtDNA

4‐Hydroxynonenal (HNE) is an important product of plasma membrane lipid peroxidation, which is a cause of cell and tissue injury. Mitochondrial DNA (mtDNA)‐depleted ρ(0) cells were established using human cervical cancer and oral squamous cell carcinoma cell lines. We investigated the effect of reac...

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Detalles Bibliográficos
Autores principales: Tomita, Kazuo, Takashi, Yuko, Ouchi, Yuya, Kuwahara, Yoshikazu, Igarashi, Kento, Nagasawa, Taisuke, Nabika, Hideki, Kurimasa, Akihiro, Fukumoto, Manabu, Nishitani, Yoshihiro, Sato, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726706/
https://www.ncbi.nlm.nih.gov/pubmed/31314163
http://dx.doi.org/10.1111/cas.14132