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Arctigenin Attenuates Tumor Metastasis Through Inhibiting Epithelial–Mesenchymal Transition in Hepatocellular Carcinoma via Suppressing GSK3β-Dependent Wnt/β-Catenin Signaling Pathway In Vivo and In Vitro

Arctigenin (ARG) has been reported to be a bioactive lignan from Arctium lappa exerting various activities including anti-cancer and immune-regulation. The present study aimed to investigate the anti-metastasis activity and mechanism of ARG against hepatocellular carcinoma in vitro and in vivo. The...

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Detalles Bibliográficos
Autores principales: Lu, Zheng, Chang, Lingling, Zhou, Hongbo, Liu, Xiaoqiang, Li, Yinqian, Mi, Tiejun, Tong, Dewen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726742/
https://www.ncbi.nlm.nih.gov/pubmed/31555129
http://dx.doi.org/10.3389/fphar.2019.00937