ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer

Poor prognosis in pancreatic cancer (PanCa) is partially due to chemoresistance to gemcitabine (GEM). Glucose metabolism has been revealed to contribute to the therapeutic resistance and pluripotent state of PanCa cells. However, few studies have focused on the effects of GEM on cancer cell metaboli...

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Detalles Bibliográficos
Autores principales: Zhao, Hengqiang, Wu, Shihong, Li, Hehe, Duan, Qingke, Zhang, Zhengle, Shen, Qiang, Wang, Chunyou, Yin, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726755/
https://www.ncbi.nlm.nih.gov/pubmed/31508487
http://dx.doi.org/10.1016/j.omto.2019.07.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726755/
https://www.ncbi.nlm.nih.gov/pubmed/31508487
http://dx.doi.org/10.1016/j.omto.2019.07.005

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