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DNA accessibility of chromatosomes quantified by automated image analysis of AFM data

DNA compaction and accessibility in eukaryotes are governed by nucleosomes and orchestrated through interactions between DNA and DNA-binding proteins. Using QuantAFM, a method for automated image analysis of atomic force microscopy (AFM) data, we performed a detailed statistical analysis of structur...

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Detalles Bibliográficos
Autores principales: Würtz, Martin, Aumiller, Dennis, Gundelwein, Lina, Jung, Philipp, Schütz, Christian, Lehmann, Kathrin, Tóth, Katalin, Rohr, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726762/
https://www.ncbi.nlm.nih.gov/pubmed/31484969
http://dx.doi.org/10.1038/s41598-019-49163-4