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Radiotherapy activates autophagy to increase CD8(+) T cell infiltration by modulating major histocompatibility complex class-I expression in non-small cell lung cancer

OBJECTIVE: Radiotherapy is reported to enhance immune responses in cancer, but appropriate doses and mechanisms remain to be investigated. This study explored whether autophagy is involved in the regulation of major histocompatibility complex class I (MHC-I) expression and CD8(+) T cell infiltration...

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Detalles Bibliográficos
Autores principales: Zeng, Hai, Zhang, Weijia, Gong, Yan, Xie, Conghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726798/
https://www.ncbi.nlm.nih.gov/pubmed/31187666
http://dx.doi.org/10.1177/0300060519855595