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Cardioprotective effect of IGF-1 against myocardial ischemia/reperfusion injury through activation of PI3K/Akt pathway in rats in vivo

OBJECTIVE: It remains unknown whether insulin-like growth factor-1 (IGF-1) can attenuate myocardial ischemia/reperfusion (I/R) injury in vivo by activating the phosphoinositide 3-kinase/protein kinase B (PI3K/Akt) pathway. This study investigated the possible interaction of IGF-1 with the PI3K/Akt p...

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Detalles Bibliográficos
Autores principales: Liao, Yaojun, Li, Hong, Pi, Yanna, Li, Zijia, Jin, Sanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726826/
https://www.ncbi.nlm.nih.gov/pubmed/31342837
http://dx.doi.org/10.1177/0300060519857839