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Novel single‐chain variant of antibody against mesothelin established by phage library

Mesothelin (MSLN) shows increased expression in various cancer cells. For clinical application of antibodies as a positron emission tomography (PET) imaging reagent, a human shortened antibody is essential both for avoiding redundant immune responses and for providing rapid imaging. Therefore, we cl...

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Detalles Bibliográficos
Autores principales: Yakushiji, Hiromasa, Kobayashi, Kazuko, Takenaka, Fumiaki, Kishi, Yoshiro, Shinohara, Midori, Akehi, Masaru, Sasaki, Takanori, Ohno, Eiji, Matsuura, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726835/
https://www.ncbi.nlm.nih.gov/pubmed/31461572
http://dx.doi.org/10.1111/cas.14150