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Use of a Blockade-of-Binding ELISA and Microneutralization Assay to Evaluate Zika Virus Serostatus in Dengue-Endemic Areas

Zika virus (ZIKV) serological diagnostics are compromised in areas where dengue viruses (DENV) co-circulate because of their high levels of protein sequence homology. Here, we describe the characterization of a Zika blockade-of-binding ELISA (Zika BOB) and a Zika microneutralization assay (Zika MN)...

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Detalles Bibliográficos
Autores principales: Nascimento, Eduardo J. M., Bonaparte, Matthew I., Luo, Ping, Vincent, Timothy S., Hu, Branda, George, James K., Áñez, Germán, Noriega, Fernando, Zheng, Lingyi, Huleatt, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726926/
https://www.ncbi.nlm.nih.gov/pubmed/31392955
http://dx.doi.org/10.4269/ajtmh.19-0270