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Psychosocial Stress Induces Schizophrenia-Like Behavior in Mice With Reduced MMP-9 Activity

Understanding gene-environment interactions in the pathogenesis of schizophrenia remains a major research challenge. Matrix metalloproteinase-9 (MMP-9) has been previously implicated in the pathophysiology of schizophrenia. In the present study, adolescent Mmp-9 heterozygous mice, with a genetically...

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Detalles Bibliográficos
Autores principales: Vafadari, Behnam, Mitra, Shiladitya, Stefaniuk, Marzena, Kaczmarek, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726971/
https://www.ncbi.nlm.nih.gov/pubmed/31555105
http://dx.doi.org/10.3389/fnbeh.2019.00195