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Postinjury Inhibition of miR-181a Promotes Restoration of Hippocampal CA1 Neurons after Transient Forebrain Ischemia in Rats

The cellular and molecular mechanisms regulating postinjury neurogenesis in the adult hippocampus remain undefined. We have previously demonstrated that preinjury treatment with anti-microRNA (miR)-181a preserved neurons and prevented astrocyte dysfunction in the hippocampal cornu ammonis-1 (CA1) fo...

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Detalles Bibliográficos
Autores principales: Griffiths, Brian B., Ouyang, Yi-Bing, Xu, Lijun, Sun, Xiaoyun, Giffard, Rona G., Stary, Creed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727148/
https://www.ncbi.nlm.nih.gov/pubmed/31427401
http://dx.doi.org/10.1523/ENEURO.0002-19.2019