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Cigarette Smoke Reduces Fatty Acid Catabolism, Leading to Apoptosis in Lung Endothelial Cells: Implication for Pathogenesis of COPD

Endothelial cell (EC) apoptosis contributes to cigarette smoke (CS)-induced pulmonary emphysema. Metabolism of glucose, glutamine, and fatty acid is dysregulated in patients with chronic obstructive pulmonary disease (COPD). Whether CS causes metabolic dysregulation in ECs leading to development of...

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Detalles Bibliográficos
Autores principales: Gong, Jiannan, Zhao, Hui, Liu, Tanzhen, Li, Lifang, Cheng, Erjing, Zhi, Shuyin, Kong, Lufei, Yao, Hong-Wei, Li, Jianqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727183/
https://www.ncbi.nlm.nih.gov/pubmed/31555131
http://dx.doi.org/10.3389/fphar.2019.00941