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Vascularization, Oxygenation, and the Effect of Sunitinib Treatment in Pancreatic Ductal Adenocarcinoma Xenografts

The purpose of the study was to investigate vascularization, oxygenation, and the effect of sunitinib treatment in pancreatic ductal adenocarcinoma (PDAC). BxPC-3 and Capan-2 xenografts grown in dorsal window chambers were used as preclinical models of human PDAC. Tumor angiogenesis and the morpholo...

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Detalles Bibliográficos
Autores principales: Gaustad, Jon-Vidar, Simonsen, Trude G., Wegner, Catherine S., Rofstad, Einar K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727195/
https://www.ncbi.nlm.nih.gov/pubmed/31555596
http://dx.doi.org/10.3389/fonc.2019.00845