Prolines Affect the Nucleation Phase of Amyloid Fibrillation Reaction; Mutational Analysis of Human Stefin B

[Image: see text] Proline residues play a prominent role in protein folding and aggregation. We investigated the influence of single prolines and their combination on oligomerization and the amyloid fibrillation reaction of human stefin B (stB). The proline mutants influenced the distribution of oli...

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Detalles Bibliográficos
Autores principales: Hasanbašić, Samra, Taler-Verčič, Ajda, Puizdar, Vida, Stoka, Veronika, Tušek Žnidarič, Magda, Vilfan, Andrej, Berbić, Selma, Žerovnik, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727212/
https://www.ncbi.nlm.nih.gov/pubmed/30924329
http://dx.doi.org/10.1021/acschemneuro.8b00621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727212/
https://www.ncbi.nlm.nih.gov/pubmed/30924329
http://dx.doi.org/10.1021/acschemneuro.8b00621

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