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TOAST: improving reference-free cell composition estimation by cross-cell type differential analysis
In the analysis of high-throughput data from complex samples, cell composition is an important factor that needs to be accounted for. Except for a limited number of tissues with known pure cell type profiles, a majority of genomics and epigenetics data relies on the “reference-free deconvolution” me...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727351/ https://www.ncbi.nlm.nih.gov/pubmed/31484546 http://dx.doi.org/10.1186/s13059-019-1778-0 |