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A Model-System to Address the Impact of Phenotypic Heterogeneity and Plasticity on the Development of Cancer Therapies

The main challenges in developing effective anti-cancer therapies stem from the highly complex and heterogeneous nature of cancer, including the presence of multiple genetically-encoded and environmentally-induced cancer cell phenotypes within an individual. This diversity can make the development o...

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Detalles Bibliográficos
Autores principales: Jong, Eric D., Chan, Irina C. W., Nedelcu, Aurora M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727362/
https://www.ncbi.nlm.nih.gov/pubmed/31555595
http://dx.doi.org/10.3389/fonc.2019.00842