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Impact of Oxidative Lesions on the Human Telomeric G-Quadruplex
[Image: see text] Telomere attrition is closely associated with cell aging and exposure to reactive oxygen species (ROS). While oxidation products of nucleotides have been studied extensively in the past, the underlying secondary/tertiary structural changes in DNA remain poorly understood. In this w...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727377/ https://www.ncbi.nlm.nih.gov/pubmed/30657306 http://dx.doi.org/10.1021/jacs.8b12748 |