Characterization of a trans–trans Carbonic Acid–Fluoride Complex by Infrared Action Spectroscopy in Helium Nanodroplets

[Image: see text] The high Lewis basicity and small ionic radius of fluoride promote the formation of strong ionic hydrogen bonds in the complexation of fluoride with protic molecules. Herein, we report that carbonic acid, a thermodynamically disfavored species that is challenging to investigate experimentally, forms a complex with fluoride in the gas phase. Intriguingly, this complex is highly stable and is observed in abundance upon nanoelectrospray ionization of an aqueous sodium fluoride solution in the presence of gas-phase carbon dioxide. We characterize the structure and properties of the carbonic acid–fluoride complex, F(–)(H(2)CO(3)), and its deuterated isotopologue, F(–)(D(2)CO(3)), by helium nanodroplet infrared action spectroscopy in the photon energy range of 390–2800 cm(–1). The complex adopts a C(2v) symmetry structure with the carbonic acid in a planar trans–trans conformation and both OH groups forming ionic hydrogen bonds with the fluoride. Substantial vibrational anharmonic effects are observed in the infrared spectra, most notably a strong blue shift of the symmetric hydrogen stretching fundamental relative to predictions from the harmonic approximation or vibrational second-order perturbation theory. Ab initio thermostated ring-polymer molecular dynamics simulations indicate that this blue shift originates from strong coupling between the hydrogen stretching and bending vibrations, resulting in an effective weakening of the OH···F(–) ionic hydrogen bonds.