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Adipocyte deficiency of ACE2 increases systolic blood pressures of obese female C57BL/6 mice

BACKGROUND: Obesity increases the risk for hypertension in both sexes, but the prevalence of hypertension is lower in females than in males until menopause, despite a higher prevalence of obesity in females. We previously demonstrated that angiotensin-converting enzyme 2 (ACE2), which cleaves the va...

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Detalles Bibliográficos
Autores principales: Shoemaker, Robin, Tannock, Lisa R., Su, Wen, Gong, Ming, Gurley, Susan B., Thatcher, Sean E., Yiannikouris, Frederique, Ensor, Charles M., Cassis, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727421/
https://www.ncbi.nlm.nih.gov/pubmed/31484552
http://dx.doi.org/10.1186/s13293-019-0260-8