Cargando…
Human NK Cell Development: One Road or Many?
CD3(−)CD56(+) NK cells develop from CD34(+) hematopoietic progenitors (HPCs) in vivo, and this process can be recapitulated in vitro. The prevailing model is that human NK cell development occurs along a continuum whereby common lymphocyte progenitors (CLPs) gradually downregulate CD34 and upregulat...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727427/ https://www.ncbi.nlm.nih.gov/pubmed/31555287 http://dx.doi.org/10.3389/fimmu.2019.02078 |