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Human NK Cell Development: One Road or Many?
CD3(−)CD56(+) NK cells develop from CD34(+) hematopoietic progenitors (HPCs) in vivo, and this process can be recapitulated in vitro. The prevailing model is that human NK cell development occurs along a continuum whereby common lymphocyte progenitors (CLPs) gradually downregulate CD34 and upregulat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727427/ https://www.ncbi.nlm.nih.gov/pubmed/31555287 http://dx.doi.org/10.3389/fimmu.2019.02078 |