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Low dose of IL-2 combined with rapamycin restores and maintains the long-term balance of Th17/Treg cells in refractory SLE patients

BACKGROUND: The development of Systemic lupus erythematosus (SLE) has been associated with the balance of Th17 and Treg cells. IL-2 and rapamycin can influence the populations of both Th17 and Treg cells. However, it is unclear whether low dose of IL-2 and rapamycin can relieve the symptoms of SLE p...

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Detalles Bibliográficos
Autores principales: Zhao, Chunmiao, Chu, Yanfang, Liang, Zhaoyun, Zhang, Bingying, Wang, Xuxia, Jing, Xiaona, Hao, Meihua, Wang, Yiqi, An, Jia, Zhang, Xingzhe, Sun, Liguang, Chen, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727508/
https://www.ncbi.nlm.nih.gov/pubmed/31484501
http://dx.doi.org/10.1186/s12865-019-0305-0