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Targeting myeloid-derived suppressor cells in combination with primary mammary tumor resection reduces metastatic growth in the lungs

BACKGROUND: Solid tumors produce proteins that can induce the accumulation of bone marrow-derived cells in various tissues, and these cells can enhance metastatic tumor growth by several mechanisms. 4T1 murine mammary tumors are known to produce granulocyte colony-stimulating factor (G-CSF) and incr...

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Detalles Bibliográficos
Autores principales: Bosiljcic, Momir, Cederberg, Rachel A., Hamilton, Melisa J., LePard, Nancy E., Harbourne, Bryant T., Collier, Jenna L., Halvorsen, Elizabeth C., Shi, Rocky, Franks, S. Elizabeth, Kim, Ada Y., Banáth, Judit P., Hamer, Mark, Rossi, Fabio M., Bennewith, Kevin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727565/
https://www.ncbi.nlm.nih.gov/pubmed/31488209
http://dx.doi.org/10.1186/s13058-019-1189-x