Cargando…
Targeting myeloid-derived suppressor cells in combination with primary mammary tumor resection reduces metastatic growth in the lungs
BACKGROUND: Solid tumors produce proteins that can induce the accumulation of bone marrow-derived cells in various tissues, and these cells can enhance metastatic tumor growth by several mechanisms. 4T1 murine mammary tumors are known to produce granulocyte colony-stimulating factor (G-CSF) and incr...
Autores principales: | Bosiljcic, Momir, Cederberg, Rachel A., Hamilton, Melisa J., LePard, Nancy E., Harbourne, Bryant T., Collier, Jenna L., Halvorsen, Elizabeth C., Shi, Rocky, Franks, S. Elizabeth, Kim, Ada Y., Banáth, Judit P., Hamer, Mark, Rossi, Fabio M., Bennewith, Kevin L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727565/ https://www.ncbi.nlm.nih.gov/pubmed/31488209 http://dx.doi.org/10.1186/s13058-019-1189-x |
Ejemplares similares
-
SHIP represses lung inflammation and inhibits mammary tumor metastasis in BALB/c mice
por: Hamilton, Melisa J., et al.
Publicado: (2015) -
Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth
por: Cederberg, Rachel A., et al.
Publicado: (2022) -
CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development
por: Melese, Etienne S., et al.
Publicado: (2021) -
Selective extracellular vesicle exclusion of miR-142-3p by oral cancer cells promotes both internal and extracellular malignant phenotypes
por: Dickman, Christopher T.D., et al.
Publicado: (2017) -
Germinal center hypoxia in tumor-draining lymph nodes negatively regulates tumor-induced humoral immune responses in mouse models of breast cancer
por: Firmino, Natalie S, et al.
Publicado: (2021)