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Co-administration of iloprost and eptifibatide in septic shock (CO-ILEPSS)—a randomised, controlled, double-blind investigator-initiated trial investigating safety and efficacy

BACKGROUND: Part of the pathophysiology in septic shock is a progressive activation of the endothelium and platelets leading to widespread microvascular injury with capillary leakage, microthrombi and consumption coagulopathy. Modulating the inflammatory response of endothelium and thrombocytes migh...

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Detalles Bibliográficos
Autores principales: Berthelsen, Rasmus Ehrenfried, Ostrowski, Sisse Rye, Bestle, Morten Heiberg, Johansson, Per Ingemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727583/
https://www.ncbi.nlm.nih.gov/pubmed/31488213
http://dx.doi.org/10.1186/s13054-019-2573-8