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Co-administration of iloprost and eptifibatide in septic shock (CO-ILEPSS)—a randomised, controlled, double-blind investigator-initiated trial investigating safety and efficacy
BACKGROUND: Part of the pathophysiology in septic shock is a progressive activation of the endothelium and platelets leading to widespread microvascular injury with capillary leakage, microthrombi and consumption coagulopathy. Modulating the inflammatory response of endothelium and thrombocytes migh...
Autores principales: | Berthelsen, Rasmus Ehrenfried, Ostrowski, Sisse Rye, Bestle, Morten Heiberg, Johansson, Per Ingemar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727583/ https://www.ncbi.nlm.nih.gov/pubmed/31488213 http://dx.doi.org/10.1186/s13054-019-2573-8 |
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