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Noninvasive and Quantitative Monitoring of the Distributions and Kinetics of MicroRNA-Targeting Molecules in Vivo by Positron Emission Tomography

[Image: see text] MicroRNAs (miRNAs) are endogenous, small, noncoding ribonucleic acids (RNAs) that bind to the 3′ untranslated regions of messenger RNAs (mRNAs) and induce translational repression or mRNA degradation. Although numerous studies have reported that miRNAs are of potential use for dise...

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Detalles Bibliográficos
Autores principales: Mäkilä, Jussi, Kiviniemi, Anu, Saanijoki, Tiina, Liljenbäck, Heidi, Käkelä, Meeri, Jadhav, Satish, Poijärvi-Virta, Päivi, Lönnberg, Harri, Laitala-Leinonen, Tiina, Virta, Pasi, Roivainen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727608/
https://www.ncbi.nlm.nih.gov/pubmed/30865461
http://dx.doi.org/10.1021/acs.molpharmaceut.8b01169