Comprehensive Landscape of Active Deubiquitinating Enzymes Profiled by Advanced Chemoproteomics

Enzymes that bind and process ubiquitin, a small 76-amino-acid protein, have been recognized as pharmacological targets in oncology, immunological disorders, and neurodegeneration. Mass spectrometry technology has now reached the capacity to cover the proteome with enough depth to interrogate entire...

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Detalles Bibliográficos
Autores principales: Pinto-Fernández, Adán, Davis, Simon, Schofield, Abigail B., Scott, Hannah C., Zhang, Ping, Salah, Eidarus, Mathea, Sebastian, Charles, Philip D., Damianou, Andreas, Bond, Gareth, Fischer, Roman, Kessler, Benedikt M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727631/
https://www.ncbi.nlm.nih.gov/pubmed/31555637
http://dx.doi.org/10.3389/fchem.2019.00592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727631/
https://www.ncbi.nlm.nih.gov/pubmed/31555637
http://dx.doi.org/10.3389/fchem.2019.00592

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