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Chromosome misalignment is associated with PLK1 activity at cenexin-positive mitotic centrosomes

The mitotic kinase, polo-like kinase 1 (PLK1), facilitates the assembly of the two mitotic spindle poles, which are required for the formation of the microtubule-based spindle that ensures appropriate chromosome distribution into the two forming daughter cells. Spindle poles are asymmetric in compos...

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Detalles Bibliográficos
Autores principales: Colicino, Erica G., Stevens, Katrina, Curtis, Erin, Rathbun, Lindsay, Bates, Michael, Manikas, Julie, Amack, Jeffrey, Freshour, Judy, Hehnly, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727634/
https://www.ncbi.nlm.nih.gov/pubmed/31042116
http://dx.doi.org/10.1091/mbc.E18-12-0817