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Chromosome misalignment is associated with PLK1 activity at cenexin-positive mitotic centrosomes
The mitotic kinase, polo-like kinase 1 (PLK1), facilitates the assembly of the two mitotic spindle poles, which are required for the formation of the microtubule-based spindle that ensures appropriate chromosome distribution into the two forming daughter cells. Spindle poles are asymmetric in compos...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727634/ https://www.ncbi.nlm.nih.gov/pubmed/31042116 http://dx.doi.org/10.1091/mbc.E18-12-0817 |